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L-cysteinyl-[PchF_non-ribosomal_peptide_synthase] + hydroxyphenyl-thiazolinyl-[PchE_non-ribosomal_peptide_synthase] <=> hydroxyphenyl-4,2-bis-thiazolinyl-[PchF_non-ribosomal_peptide_synthase] + H2O + [PchE_non-ribosomal_peptide_synthase] + H+
|
not assigned
|
–
|
|
MetaCyc:
RXN-11120
|
|
|
|
H+ + salicylate + ATP <=> (2-hydroxybenzoyl)adenylate + diphosphate
|
2.7.7.58
(2,3-dihydroxybenzoyl)adenylate synthase
6.2.1.61
salicylate---[aryl-carrier protein] ligase
6.2.1.65
salicylate---CoA ligase
|
–
–
–
|
|
BRENDA:
BR53008;
BR53122
KEGG:
R12640
MetaCyc:
RXN-11113
|
|
|
|
L-cysteine + ATP + H+ <=> (L-cysteinyl)adenylate + diphosphate
|
not assigned
|
–
|
|
MetaCyc:
RXN-11115
|
|
|
|
(L-cysteinyl)adenylate + [PchF_non-ribosomal_peptide_synthase_protein] <=> L-cysteinyl-[PchF_non-ribosomal_peptide_synthase] + AMP + H+
|
not assigned
|
–
|
|
MetaCyc:
RXN-11117
|
|
|
|
(L-cysteinyl)adenylate + [PchE_non-ribosomal_peptide_synthase] <=> L-cysteinyl-[PchE_non-ribosomal_peptide_synthase] + AMP + H+
|
not assigned
|
–
|
|
MetaCyc:
RXN-11125
|
|
|
|
hydroxyphenyl-4,2-bis-thiazolinyl-[PchF_non-ribosomal_peptide_synthase] + NADPH + H+ <=> N-desmethyl-pyochelin-[PchF_non-ribosomal_peptide_synthase] + NADP+
|
not assigned
|
–
|
|
MetaCyc:
RXN-11121
|
|
|
|
salicyl-L-cysteinyl-[PchE_non-ribosomal_peptide_synthas] <=> hydroxyphenyl-thiazolinyl-[PchE_non-ribosomal_peptide_synthase] + H2O
|
not assigned
|
–
|
|
MetaCyc:
RXN-11118
|
|
|
|
pyochelinyl-[PchF_non-ribosomal_peptide_synthase] + H2O <=> pyochelin + [PchF_non-ribosomal_peptide_synthase_protein] + H+
|
not assigned
|
–
|
|
MetaCyc:
RXN-11123
|
|
|
|
(2-hydroxybenzoyl)adenylate + [PchE_non-ribosomal_peptide_synthase] <=> salicyl-[PchE_non-ribosomal_peptide_synthase] + AMP + H+
|
not assigned
|
–
|
|
MetaCyc:
RXN-19466
|
|
|
|
S-adenosyl-L-methionine + N-desmethyl-pyochelin-[PchF_non-ribosomal_peptide_synthase] <=> pyochelinyl-[PchF_non-ribosomal_peptide_synthase] + S-adenosyl-L-homocysteine + H+
|
not assigned
|
–
|
|
MetaCyc:
RXN-11122
|
|
|
|
salicyl-[PchE_non-ribosomal_peptide_synthase] + L-cysteinyl-[PchE_non-ribosomal_peptide_synthase] <=> salicyl-L-cysteinyl-[PchE_non-ribosomal_peptide_synthas] + [PchE_non-ribosomal_peptide_synthase] + H+
|
not assigned
|
–
|
|
MetaCyc:
RXN-19469
|
|