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pyochelin biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
L-cysteinyl-[PchF_non-ribosomal_peptide_synthase] + hydroxyphenyl-thiazolinyl-[PchE_non-ribosomal_peptide_synthase] <=> hydroxyphenyl-4,2-bis-thiazolinyl-[PchF_non-ribosomal_peptide_synthase] + H2O + [PchE_non-ribosomal_peptide_synthase] + H+ not assigned

H+ + salicylate + ATP <=> (2-hydroxybenzoyl)adenylate + diphosphate 2.7.7.58 (2,3-dihydroxybenzoyl)adenylate synthase
6.2.1.61 salicylate---[aryl-carrier protein] ligase
6.2.1.65 salicylate---CoA ligase



L-cysteine + ATP + H+ <=> (L-cysteinyl)adenylate + diphosphate not assigned

(L-cysteinyl)adenylate + [PchF_non-ribosomal_peptide_synthase_protein] <=> L-cysteinyl-[PchF_non-ribosomal_peptide_synthase] + AMP + H+ not assigned

(L-cysteinyl)adenylate + [PchE_non-ribosomal_peptide_synthase] <=> L-cysteinyl-[PchE_non-ribosomal_peptide_synthase] + AMP + H+ not assigned

hydroxyphenyl-4,2-bis-thiazolinyl-[PchF_non-ribosomal_peptide_synthase] + NADPH + H+ <=> N-desmethyl-pyochelin-[PchF_non-ribosomal_peptide_synthase] + NADP+ not assigned

salicyl-L-cysteinyl-[PchE_non-ribosomal_peptide_synthas] <=> hydroxyphenyl-thiazolinyl-[PchE_non-ribosomal_peptide_synthase] + H2O not assigned

pyochelinyl-[PchF_non-ribosomal_peptide_synthase] + H2O <=> pyochelin + [PchF_non-ribosomal_peptide_synthase_protein] + H+ not assigned

(2-hydroxybenzoyl)adenylate + [PchE_non-ribosomal_peptide_synthase] <=> salicyl-[PchE_non-ribosomal_peptide_synthase] + AMP + H+ not assigned

S-adenosyl-L-methionine + N-desmethyl-pyochelin-[PchF_non-ribosomal_peptide_synthase] <=> pyochelinyl-[PchF_non-ribosomal_peptide_synthase] + S-adenosyl-L-homocysteine + H+ not assigned

salicyl-[PchE_non-ribosomal_peptide_synthase] + L-cysteinyl-[PchE_non-ribosomal_peptide_synthase] <=> salicyl-L-cysteinyl-[PchE_non-ribosomal_peptide_synthas] + [PchE_non-ribosomal_peptide_synthase] + H+ not assigned

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